Journal: Scientific Reports
Article Title: Constitutive depletion of Slc34a2 /NaPi-IIb in rats causes perinatal mortality
doi: 10.1038/s41598-021-86874-z
Figure Lengend Snippet: ( A ) Plasma Pi, ( B ) plasma Ca 2+ , ( C ) plasma intact FGF-23 and ( D ) plasma 1,25(OH) 2 vitamin D 3 of wild type (n = 4) and heterozygous (n = 5) Slc34a2 rats fed standard chow (NPD) or challenged for 3 days with low Pi diet (LPD). Data are presented as means ± SEM. Statistical significance was calculated by ANOVA-Bonferroni. * P ≤ 0.05, ** P ≤ 0.01, *** P ≤ 0.001, and **** P ≤ 0.0001.
Article Snippet: Rats with constitutive depletion of NaPi-IIb/ Slc34a2 were generated by Charles River using a Crispr-Cas approach.
Techniques: Clinical Proteomics